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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAD1L1 All Species: 21.82
Human Site: T680 Identified Species: 48
UniProt: Q9Y6D9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6D9 NP_001013858.1 718 83067 T680 S K M Q L L E T E F S H T V G
Chimpanzee Pan troglodytes XP_518933 718 83078 T680 S K M Q L L E T E F S H T V G
Rhesus Macaque Macaca mulatta XP_001102100 956 108383 T680 S K M Q L L E T E F S H T V D
Dog Lupus familis XP_852066 833 95008 T795 T K M Q L L E T A F S R T I Q
Cat Felis silvestris
Mouse Mus musculus Q9WTX8 717 83523 T679 S K M Q L L E T E F S R S V P
Rat Rattus norvegicus NP_001102857 717 83311 T679 S K M Q L L E T E F S R S V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425231 717 83910 N679 G K M Q L L E N E F S R T V R
Frog Xenopus laevis P10999 583 67273 R546 C A E R T L Y R V I G E E G E
Zebra Danio Brachydanio rerio NP_957206 323 37683 D286 S M Q L L E T D F S R T L T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796080 709 81997 F672 M D L L A N E F S S S L S H M
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001151757 716 81232 Y678 T N I V V N D Y T S Q Q E I A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 73.1 72.3 N.A. 81 83 N.A. N.A. 69.9 20.6 27.9 N.A. N.A. N.A. N.A. 33.1
Protein Similarity: 100 99.5 73.8 80.1 N.A. 90.8 92.1 N.A. N.A. 84.6 40.5 37.7 N.A. N.A. N.A. N.A. 59.3
P-Site Identity: 100 100 93.3 66.6 N.A. 80 80 N.A. N.A. 73.3 6.6 20 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 80 N.A. 86.6 86.6 N.A. N.A. 73.3 13.3 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. 23.2 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 46.2 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 0 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 0 0 10 0 0 0 0 0 10 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 10 10 0 0 0 0 0 0 10 % D
% Glu: 0 0 10 0 0 10 73 0 55 0 0 10 19 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 10 64 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 10 0 0 10 28 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 28 0 10 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 10 0 0 0 19 0 % I
% Lys: 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 19 73 73 0 0 0 0 0 10 10 0 0 % L
% Met: 10 10 64 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 10 0 0 0 19 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % P
% Gln: 0 0 10 64 0 0 0 0 0 0 10 10 0 0 10 % Q
% Arg: 0 0 0 10 0 0 0 10 0 0 10 37 0 0 10 % R
% Ser: 55 0 0 0 0 0 0 0 10 28 73 0 28 0 0 % S
% Thr: 19 0 0 0 10 0 10 55 10 0 0 10 46 10 0 % T
% Val: 0 0 0 10 10 0 0 0 10 0 0 0 0 55 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _